Correlation between vitamin D status in mothers and their neonates in an Iranian population

Background and Objective: There has been a resurgence of nutritional rickets in children in many developing countries. Furthermore, Vitamin D deficiency is one of the major health problems and unexpectedly has a high prevalence in sunny countries (e.g. Middle East). In order to find out the association between vitamin D deficiencies in mothers and their neonates, we designed this study. Methods:&nbsp;In a cross-sectional study, 49 pregnant women were recruited from Ali-Asghar children&rsquo;s hospital in Tehran, in 2015. All blood samples were assayed for 25-hydroxyvitamin D3, calcium, phosphorus, parathyroid hormone, alkaline phosphatase and creatinine. Vitamin D deficiency defined as levels of 25(OH) D < 20 ng/ml for mothers and newborns. Results:&nbsp;The mean&plusmn;SD 25OHD levels of the mothers and their neonates were 26.1&plusmn;8.44 ng/mL and 17.23 &plusmn;10.36 ng/Ml, respectively. Serum 25OHD of the mothers and their neonates were significantly correlated (r = 0.446, P< 0.001). Conclusion:&nbsp;We found a significant correlation between vitamin D deficiency in mothers and their neonates. We think it is necessary to reconsider the recommendation of vitamin D supplementation for women during pregnancy.